Paper Published in JBO!

Monte Carlo simulations support non-Cerenkov radioluminescence production in tissue

Nicole L. Ackerman
Agnes Scott College, Department of Physics and Astronomy, Decatur, Georgia (United States)
Federico Boschi
University of Verona, Department of Computer Science, Verona (Italy)
Antonello E. Spinelli
San Raffaele Scientific Institute, Centre for Experimental Imaging, Department of Medical Physics, M (Italy)
J. of Biomedical Optics, 22(8), 086002 (2017). doi:10.1117/1.JBO.22.8.086002
Abstract
There is experimental evidence for the production of non-Cerenkov radioluminescence in a variety of materials, including tissue. We constructed a Geant4 Monte Carlo simulation of the radiation from P 32 and Tc99 m interacting in chicken breast and used experimental imaging data to model a scintillation-like emission. The same radioluminescence spectrum is visible from both isotopes and cannot otherwise be explained through fluorescence or filter miscalibration. We conclude that chicken breast has a near-infrared scintillation-like response with a light yield three orders of magnitude smaller than BGO.